Sartorius' single-use bioreactors from 15 mL working volume with Ambr® 15 to Biostat® STR 2,000 L have been developed to ensure easy and straightforward scale-up and scale-down. Combined with unprecedented high performance even at large scale this makes these products perfectly suitable to serve all your current and future needs from process development to commercial production phases.

Comparing cultures in identically-sized, multi-parallel bioreactors allow scientists to find out more process information in a shorter timeline. Multiple experiments can be set up to evaluate different culture strains and the effect of process parameters, such as temperature, feeding, media composition, gassing rates and inoculation densities.

The industry-leading range of Ambr® multi-parallel bioreactors has been developed to take you through the early steps of your upstream process from cell or strain selection, through to process optimization. The technology ensures optimum scalability of your processes, as the design of the bioreactors means that functionality translates well into systems such as the Biostat STR® 2000 and larger.

Sartorius® offers you scalable benchtop solutions for the development of your bioprocess. Whether you perform batch, fed-batch or perfusion processes, Sartorius® has a wide range of stirred-tank bioreactors and fermenters. You can use the benchtop bioreactors for cell cultivation as well as for microbial fermentation. Autoclavable culture vessels are available from 1 L to 10 L and single use vessels of 250 mL and 2 L.

The Sartorius® portfolio of stainless steel fermenters and bioreactors includes standard products from 5 L to 200 L and customized engineering solutions up to 2,000 L. Sartorius' long-standing process knowledge combined with the unrivaled quality of the fermenter systems yields state-of-the-art bioprocess equipment matching your highly demanding applications. Sartorius® systems are dedicated to process development, pilot scale and small production scale processing for microbial and cell culture fermentation. As part of the comprehensive Sartorius Biostat® bioreactor portfolio, stainless steel fermenters can be easily integrated as a component of hybrid systems. An additional benefit is provided through the implementation of advanced process analytical technologies (BioPAT®) in the control and regulation loop of the DCU bioreactors.

Sartorius’ expertise in automation and engineering and detailed understanding of biopharmaceutical and industrial processes ensures robust, reliable and scalable systems suitable for even the most demanding microbial cultures. Advanced analytical capabilities from the PAT portfolio including online pH, off-gas and biomass measurement allow predictive process modeling and control. Intuitive software and powerful chemometrics tools assist with process understanding and enable a Quality by Design approach for optimization and mapping of the process design space.

Sartorius Stedim Biotech supplies the widest range of cell culture bioreactors for research and development work through to pilot and cGMP Manufacture. Optimally suited for production of mAbs, vaccines, recombinant proteins, and in cell and gene therapy applications, the systems support many different types of cell lines and processes including batch, fed-batch, and perfusion | continuous processing. Sartorius® delivers solutions for suspension as well as adherent microcarrier cultures, including those which require low shear and specialist mixing capabilities.