APIS Breast Cancer Subtyping Kit (RUO*)
The APIS Breast Cancer Subtyping Kit is a highly reproducible, RT-qPCR-based kit for detecting mRNA expression of standard breast cancer biomarkers (HER2, ER, PR, Ki67) and novel proliferative biomarkers from core-needle biopsy (CNB) or resected formalin-fixed paraffin embedded (FFPE) breast tumour tissue. Receptor tyrosine-protein kinase erbB-2 (HER2), oestrogen receptor (ER), progesterone receptor (PR), and marker of proliferation (Ki67) biomarkers play a key role in breast cancer.
The kit also includes a novel four-gene proliferative signature that comprises four markers (MKI67, CCNA2, KIF23, and PCNA) associated with proliferation. These markers are expressed throughout all cell cycle stages, providing a more precise representation of tumour proliferation.
*APIS Breast Cancer Subtyping Kit is for Research Use Only (RUO), not for use in diagnostic procedures.
Features of the Assay
• Reliable and highly precise detection of HER2, ER, PR & Ki67 mRNA expression levels
• Reproducible and consistent results across multiple samples
• Novel four-gene proliferative signature provides a more precise representation of tumour proliferation
• Quick results in less than 5 hours when processing 10 samples
Specifications:
Kit size: 24 Samples in duplicate plus controls
Specimen requirements:
- 10 µM FFPE core needle biopsy or resected tissue section
- Neoplastic cells ≥20%
Turnaround time: Delivering precise results for standard biomarkers and a novel proliferative signature in less than 5 hours when processing 10 samples.
Additional information: https://www.biocartis.com/en/r...
