Label antibodies, small molecules, proteins, or peptides with IVISense NIR fluorescent dyes.
Revvity’s IVISense™ fluorescent dyes (VivoTag®) for labeling antibodies, small molecules, proteins, or peptides are designed specifically to enable customized development of novel superbright fluorescent imaging agents. Dye properties, such as excellent brightness, hydrolytic stability, and photostability, as well as selection for minimal interaction with biological tissue for no potential loss of specificity, have been optimized and validated for use in in vivo or in vitro imaging.
Available as NHS esters or maleimide reactive dyes for conjugation to either free amine (-NH3) or free thiol (-SH) containing molecules. Conjugate an optimal 1-3 dyes onto your protein or choose self-quenching dyes to make your own custom fluorogenic probes.
IVISense 750 MAL Fluorescent Self-Quenching Dye is a thiol (-SH, sulfhydryl) reactive, maleimide-containing NIR fluorochrome for labeling small molecules. Its superior brightness makes it particularly well suited for a wide range of both in vivo and in vitro imaging applications using labeled thiol-containing molecules.
It is optimized for single molecule loading, such that labeling a protein with multiple IVISense Self-Quenching Dye molecules will cause a shift in the absorbance of the dye and reduce the signal. Therefore, only choose IVISense Self-Quenching Dyes if your labeling ratio of dye:protein will be 1:1.
Optimized for use with IVIS™ fluorescence imaging systems with expanded wavelength capabilities, IVISense dyes enable quantitative imaging of up to four channels and four different biomarkers of interest in vivo.
Unit size 1 mg
For research use only. Not for use in diagnostic procedures.
