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SKU NEV11079

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.

IVISense Renin 680 FAST is a member of a family of activatable fluorescent imaging agents comprising a novel architecture, termed F.A.S.T. (Fluorescent Activatable Sensor Technology), that confers an improved pharmacokinetic profile with a broader range of early imaging timepoints. This architecture also offers higher target specific signal with reduced background.

IVISense Renin 680 FAST is a Renin activatable agent that is optically silent upon injection and produces fluorescent signal after cleavage by renin produced in the kidneys. The Renin-Angiotensin System (RAS) is the hormone system involved in regulating blood pressure and fluid balance in the body.

IVISense Renin 680 FAST is recognized and activated by rodent forms of renin in preclinical animal models. It may be used to monitor abnormal RAS function, progression of disease and the efficacy of therapeutic treatment in disorders such as hypertension and cardiovascular disease and some neurological diseases.

For laboratory use only. This product is intended for animal research only and not for use in humans.

Specifications

Specifications

Documents

In_Vivo_Agents.pdf

Perkin Elmer In Vivo Imaging Agents Brochure

EN | 4.238 MB

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