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ProSense 680 Fluorescent Imaging Agent

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SKU NEV10003

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Proteases perform a fundamental role in protein regulation. Altered activity of lysosomal cathepsins, a class of protease, can indicate many disease-related processes, such as those involved in cancer, inflammation, arthritis, cardiovascular and many others. The ability to detect and quantify normal as well as altered protease cathepsin activity in vivo allows the progress and severity of these disease states to be tracked and interrogated over time. PerkinElmer’s ProSense® imaging agents are protease activatable NIR fluorescent probes that are optically silent in their intact state and become highly fluorescent following protease-mediated cleavage and activation. It is available in 3 formats; 680, 750 EX, and 750 FAST.

IVISense Pan Cathepsin 680 is Perkin Elmer’s original “Smart” cathepsin probe; rather than targeting all protease, smart probes become fluorescent only after enzymatic cleavage, which keeps background down and allows detection of activated protease. 24h imaging at 680 nm.

For laboratory use only. This product is intended for animal research only and not for use in humans.

Specifications

Specifications
Product Brand Name

ProSense

Therapeutic Area

Atherosclerosis, Arthritis, Inflammation, Oncology/Cancer

Wavelength

680 nm

Unit Size

1 Vial (10 doses)

Documents

In_Vivo_Agents.pdf

Perkin Elmer In Vivo Imaging Agents Brochure

EN | 4.238 MB

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