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MMPSense 680 Fluorescent Imaging Agent

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SKU NEV10126

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Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

PerkinElmer’s MMPSense NIR activatable fluorescence agents are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

MMPSense 680 is excited by 680 + 10 nm excitation light, and emits at 700 + 10 nm. MMPSense 680 has an optimal imaging window of 24-36 hours after injection, allowing workflow flexibility in acquiring data in large animal cohorts. Including MMPSense 680 in careful experimental design allows for multiplexing with other channels and/or imaging times, and so can be paired with other probes to achieve maximum efficiency and flexibility in imaging.

For laboratory use only. This product is intended for animal research only and not for use in humans.

Specifications

Specifications
Product Brand Name

MMPSense

Therapeutic Area

Atherosclerosis, Arthritis, Inflammation, Oncology/Cancer

Wavelength

680 nm

Unit Size

1 Vial (10 doses)

Documents

In_Vivo_Agents.pdf

Perkin Elmer In Vivo Imaging Agents Brochure

EN | 4.238 MB

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