Create new account

Register now and get additional benefits:
  • Personal prices
  • Delivery tracking
  • Pre-filled and quick checkout
  • Order history and fast re-ordering
  • Exact product stock status
Cart

Your cart is empty, just add some products

This is a fantastic opportunity to fill the cart with something really special!

Estimated shipping

€0.00

Total: €0.00

image/svg+xml Log in / Register
Log in or register
Log in Create account
Register now and get additional benefits:
  • Personal prices
  • Delivery tracking
  • Pre-filled and quick checkout
  • Order history and fast re-ordering
  • Exact product stock status
1-placeholder

SKU NEV10873

Integrins are a superfamily of transmembrane cell surface receptors that mediate signal transduction, cell-to-cell interaction, and cell-to-extracellular matrix adhesion - key processes for healthy cells as well as progression of disease states such as atherosclerosis and cancer, where integrins contribute to angiogenesis, tumorigenesis, and metastasis.

Among this superfamily, αvβ3 integrin holds promise as a therapeutic target in areas such as immuno-oncology, where αvβ3 integrin may prevent tumors from evading the immune system. PerkinElmer's IVISense Integrin Receptor 750 Fluorescent Probes are designed to target αvβ3 integrin for monitoring tumor growth, angiogenesis and assessing treatment efficacy.

IntegriSense 750 fluorescent imaging agent for in vivo detection of αvβ3 integrin is a low molecular weight peptidomimetic antagonist coupled to a red fluorochrome. This validated, high affinity (Kd = 4.2 nM) fluorescent probe has improved circulation half-life and specificity over RDG peptide-based agents, with selectivity 5-20x for αvβ3 integrin, for precise detection of αvβ3 integrins. IntegriSense 750 integrin-targeted molecular imaging agent allows non-invasive imaging to better understand biological pathways, and disease biology and progression. Including IntegriSense 750 fluorescent probe in careful experimental design allows for multiplexing with other channels and/or imaging times, and can be paired with other probes to achieve maximum efficiency and flexibility in your imaging studies.

For laboratory use only. This product is intended for animal research only and not for use in humans.

Specifications

Specifications

Documents

In_Vivo_Agents.pdf

Perkin Elmer In Vivo Imaging Agents Brochure

EN | 4.238 MB

Download

Recently viewed

Company

Nova Natura UAB

Chemijos G. 11, LT-51347,
Kaunas, Lithuania

nova@novabio.lt
Phone: +370 (620) 70159

Reg No 305063819

Nova Natura OÜ

Kanali tee 6, 10112,
Tallinn, Estonia

nova@novabio.ee
Phone: +372 5656 0050

Reg No 14758203

Let’s stay in touch

Join our newsletter!
Certification9001